DuraGraft® Vascular Conduit Solution

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Studies show that standard storage solutions like saline/blood can be associated with endothelial damage and loss of cell viability. DuraGraft is the first FDA-cleared solution in its class, indicated for flushing and storage of vascular grafts. Its mechanism of action is the reduction of oxidative damage to maintain structural and functional integrity during the harvesting and grafting interval. 

No. DuraGraft is a one-time intraoperative treatment. It replaces your current flushing and storage solution. There is no additional equipment or complex mixing required.

Immediately upon harvest. Oxidative damage begins the moment blood flow is cut off. DuraGraft is designed to be used as the primary flushing solution right after the vein is removed to preserve structural integrity during the ischemic window.

Wall thickening (intimal hyperplasia) is a precursor to graft failure. Clinical data demonstrated that veins stored in DuraGraft exhibited significantly less wall thickening at 12 months compared to those stored in saline.

Unlike saline, DuraGraft utilizes specific salts and organic components (normal constituents of blood) to create a non-oxidizing, pH-balanced environment (pH 7.4). This mechanism reduces oxidative damage and helps maintain the structural and functional integrity of the graft during ischemia.